Home / Generic availability / Exenatide
When will generic Exenatide be available?
Based on the patents and exclusivity the FDA lists today, generic exenatide cannot be marketed in the United States before 2031-04-04, when the last listed protection expires.
Patents listed with the FDA
38 unexpired or current listing(s).
| Patent | Expires | Covers | Product |
|---|---|---|---|
| 6515117 | 2025-10-04 | drug substance, drug product | BYDUREON BCISE |
| 6515117 | 2025-10-04 | drug substance, drug product | BYDUREON |
| 6515117 | 2025-10-04 | drug substance, drug product | BYDUREON PEN |
| 6515117*PED | 2026-04-04 | method of use | BYDUREON BCISE |
| 6515117*PED | 2026-04-04 | method of use | BYDUREON |
| 6515117*PED | 2026-04-04 | method of use | BYDUREON PEN |
| 8329648 | 2026-08-18 | method of use | BYDUREON BCISE |
| 8906851 | 2026-08-18 | method of use | BYDUREON BCISE |
| 9884092 | 2026-08-18 | method of use | BYDUREON BCISE |
| 8329648 | 2026-08-18 | method of use | BYDUREON |
| 8906851 | 2026-08-18 | method of use | BYDUREON |
| 9884092 | 2026-08-18 | method of use | BYDUREON |
| 8329648 | 2026-08-18 | method of use | BYDUREON PEN |
| 8906851 | 2026-08-18 | method of use | BYDUREON PEN |
| 9884092 | 2026-08-18 | method of use | BYDUREON PEN |
| 8329648*PED | 2027-02-18 | method of use | BYDUREON BCISE |
| 8906851*PED | 2027-02-18 | method of use | BYDUREON BCISE |
| 9884092*PED | 2027-02-18 | method of use | BYDUREON BCISE |
| 8329648*PED | 2027-02-18 | method of use | BYDUREON |
| 8906851*PED | 2027-02-18 | method of use | BYDUREON |
| 9884092*PED | 2027-02-18 | method of use | BYDUREON |
| 8329648*PED | 2027-02-18 | method of use | BYDUREON PEN |
| 8906851*PED | 2027-02-18 | method of use | BYDUREON PEN |
| 9884092*PED | 2027-02-18 | method of use | BYDUREON PEN |
| 8501698 | 2027-06-20 | method of use | BYDUREON BCISE |
| 8501698 | 2027-06-20 | drug product | BYDUREON |
| 8501698 | 2027-06-20 | drug product | BYDUREON PEN |
| 8501698*PED | 2027-12-20 | method of use | BYDUREON BCISE |
| 8501698*PED | 2027-12-20 | method of use | BYDUREON |
| 8501698*PED | 2027-12-20 | method of use | BYDUREON PEN |
| 8361972 | 2028-03-21 | method of use | BYDUREON BCISE |
| 8361972 | 2028-03-21 | method of use | BYDUREON |
| 8361972 | 2028-03-21 | method of use | BYDUREON PEN |
| 8361972*PED | 2028-09-21 | method of use | BYDUREON BCISE |
| 8361972*PED | 2028-09-21 | method of use | BYDUREON |
| 8361972*PED | 2028-09-21 | method of use | BYDUREON PEN |
| 8895033 | 2030-10-04 | drug product | BYDUREON BCISE |
| 8895033*PED | 2031-04-04 | method of use | BYDUREON BCISE |
Approved products
| Product | Type | Applicant | Approved | |
|---|---|---|---|---|
| BYETTA | Brand (NDA) | ASTRAZENECA AB | 2005-04-28 | reference listed drug |
| BYDUREON, BYDUREON PEN | Brand (NDA) | ASTRAZENECA AB | 2012-01-27 | reference listed drug |
| EXENATIDE SYNTHETIC | Generic (ANDA) | AMNEAL EU LTD | 2024-11-19 | reference standard |
| BYDUREON BCISE | Brand (NDA) | ASTRAZENECA AB | 2017-10-20 | reference listed drug |
Frequently asked questions
When will generic Exenatide be available?
Based on the patents and exclusivity the FDA lists today, generic exenatide cannot be marketed in the United States before 2031-04-04, when the last listed protection expires.
Does this date guarantee a generic launches then?
No. It is the date the last protection the FDA currently lists expires. Patents can be challenged, licensed, or designed around, which can bring a generic earlier, and new patents can be listed later. Treat it as the outer limit of the brand's protection, not a launch forecast.
What is the difference between a patent and exclusivity?
A patent is granted by the patent office and listed with the FDA by the brand. Exclusivity is granted by the FDA itself on approval. They run independently, and exclusivity can keep a generic off the market even after a patent has expired.
What is a tentative approval?
It means the FDA has reviewed a generic application and judged it acceptable, but cannot allow it to be marketed yet because patents or exclusivity are still running. It is the clearest signal that a generic is ready to launch once the dates clear.
Source: FDA Orange Book via openFDA, with tentative-approval data from Drugs@FDA. Last updated 2026-09-23. Do not rely on this page to make decisions regarding medical care; always speak to your health provider about the risks and benefits of FDA-regulated products.