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New — The Peptide Dictionary: 128 terms, explained simply
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Not sure where to start? — A 60-second quiz points you to the path that fits your goal
New explainer — Semaglutide: what the research says, made simple
Browse — Peptide guides, made simple
New — The Peptide Dictionary: 128 terms, explained simply
New guide — NAD+ for Anti-Aging: What the Science Says
New guide — GHK-Cu: the copper peptide for your skin
Not sure where to start? — A 60-second quiz points you to the path that fits your goal
New explainer — Semaglutide: what the research says, made simple
Browse — Peptide guides, made simple
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Best GLP-1 programs of 2026

Fourteen telehealth providers our peptides.io editorial team reviewed for clinician support, pricing transparency, eligibility, and compliance. Compounded GLP-1 medications are not FDA-approved — talk to your doctor.

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Common Questions

Where is peptides.io available?
peptides.io is available to users throughout the United States. We feature licensed telehealth providers that collectively operate across all 50 US states. Individual provider and medication availability may vary by state due to differing licensing requirements and state-level telehealth regulations. When you select a provider, that provider's own intake process will confirm eligibility and availability in your state before any consultation or prescription takes place.
How much weight will I lose?
Clinical trials of FDA-approved branded GLP-1 medications (such as Wegovy® and Zepbound®) have shown that patients can lose a significant percentage of body weight when these medications are combined with diet and exercise. These clinical results apply only to the FDA-approved branded products studied and do not apply to compounded formulations, which have not been evaluated by the FDA for safety or effectiveness. Individual results vary.
What is the difference between Semaglutide and Tirzepatide?
Semaglutide mimics one hormone (GLP-1) to reduce appetite. Tirzepatide mimics two hormones (GLP-1 and GIP), which may lead to potentially greater weight loss efficacy for some patients.
Is this a subscription?
Yes. Long-term consistency is key for metabolic health. Monthly subscriptions ensure you never run out of medication. You can pause or cancel at any time, but stopping the medication often leads to weight regain.
What side effects may occur?

GLP-1 medications, whether FDA-approved brand-name or compounded formulations, can cause side effects. Commonly reported side effects may include:

  • Nausea (often most pronounced when starting or increasing the dose)
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal discomfort
  • Headache
  • Fatigue

These side effects are often most noticeable during the initial weeks of treatment and during dose escalation periods. Many users report that side effects diminish as their body adjusts to the medication through a gradual titration process.