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Are there clinical trials for Abaloparatide?
Abaloparatide has 25 registered clinical trials, including 13 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Trial breakdown
By phase
| Phase 3 | 7 |
| Phase 2 | 7 |
| Phase 1 | 5 |
| Phase 4 | 3 |
| Not applicable | 1 |
By status
| Completed | 14 |
| Withdrawn | 2 |
| Recruiting | 2 |
| Not yet recruiting | 2 |
| Active, not recruiting | 2 |
| Terminated | 1 |
| Enrolling by invitation | 1 |
| Unknown status | 1 |
Active trials
- The Effect of Osteoporotic Medications on Vertebral Bone Quality ScorePhase 2 · Enrolling by invitation · 60 participants · State University of New York at Buffalo · started 2026-06-18NCT07587775
- MicroRNA and Markers and Therapeutic Response to Romosozumab and Abaloparatide in Postmenopausal OsteoporosisNot applicable · Recruiting · 42 participants · Istituto Auxologico Italiano · started 2025-08-31NCT07616401
- To Evaluate the Efficacy and Safety of Abaloparatide Injection (QLG2128) in the Treatment of Postmenopausal Women With Osteoporosis and at High Risk of FracturePhase 3 · Not yet recruiting · 282 participants · Qilu Pharmaceutical Co., Ltd. · started 2025-06NCT06898060
- A Single-center, Open, Randomized, Single-dose, Cross-over Bioequivalence Study to Evaluate the Effects of the Test Formulation Abalparatide Injection and the Reference Formulation Abalparatide Injection (Tymlos®) in Healthy Adult SubjectsPhase 1 · Not yet recruiting · 32 participants · The Affiliated Hospital of Qingdao University · started 2025-01-02NCT06753864
- Sequential Therapies After Osteoanabolic TreatmentRecruiting · 150 participants · 424 General Military Hospital · started 2023-11-25NCT06164795
- Abaloparatide Added to Ongoing Denosumab vs Continued Denosumab AlonePhase 4 · Active, not recruiting · 70 participants · Hospital for Special Surgery, New York · started 2021-02-01NCT04467983
- Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion SurgeryPhase 2 · Active, not recruiting · 96 participants · Hospital for Special Surgery, New York · started 2019-08-14NCT03841058
Most recent registered trials
- The Effect of Osteoporotic Medications on Vertebral Bone Quality ScorePhase 2 · Enrolling by invitation · 60 participants · State University of New York at Buffalo · started 2026-06-18NCT07587775
- MicroRNA and Markers and Therapeutic Response to Romosozumab and Abaloparatide in Postmenopausal OsteoporosisNot applicable · Recruiting · 42 participants · Istituto Auxologico Italiano · started 2025-08-31NCT07616401
- To Evaluate the Efficacy and Safety of Abaloparatide Injection (QLG2128) in the Treatment of Postmenopausal Women With Osteoporosis and at High Risk of FracturePhase 3 · Not yet recruiting · 282 participants · Qilu Pharmaceutical Co., Ltd. · started 2025-06NCT06898060
- A Single-center, Open, Randomized, Single-dose, Cross-over Bioequivalence Study to Evaluate the Effects of the Test Formulation Abalparatide Injection and the Reference Formulation Abalparatide Injection (Tymlos®) in Healthy Adult SubjectsPhase 1 · Not yet recruiting · 32 participants · The Affiliated Hospital of Qingdao University · started 2025-01-02NCT06753864
- Supracondylar Distal Femur Fractures and AbaloparatidePhase 4 · Withdrawn · Daniel Horwitz · started 2024-06NCT04626141
- Study to Evaluate the Efficacy and Safety of PBK_L2201 in Postmenopausal Women With OsteoporosisPhase 3 · Unknown status · 60 participants · Pharmbio Korea Co., Ltd. · started 2024-02NCT06154187
- Sequential Therapies After Osteoanabolic TreatmentRecruiting · 150 participants · 424 General Military Hospital · started 2023-11-25NCT06164795
- PTH Analog Type II Odontoid FracturePhase 2 · Terminated · 22 participants · David Lunardini · started 2022-05-18NCT04760782
- Real-world Effectiveness and Cardiovascular Safety Study of Abaloparatide in Postmenopausal WomenCompleted · 22054 participants · Radius Health, Inc. · started 2021-07-01NCT04974723
- Effect of Abaloparatide on Lumbar Disc DegenerationPhase 2 · Withdrawn · Johns Hopkins University · started 2021-03NCT03708926
- Abaloparatide Added to Ongoing Denosumab vs Continued Denosumab AlonePhase 4 · Active, not recruiting · 70 participants · Hospital for Special Surgery, New York · started 2021-02-01NCT04467983
- Study to Evaluate and Compare the Bioequivalence of Two Abaloparatide-sMTS Treatments in Healthy Women.Phase 1 · Completed · 36 participants · Radius Health, Inc. · started 2020-11-16NCT04936984
Frequently asked questions
Are there clinical trials for Abaloparatide?
Abaloparatide has 25 registered clinical trials, including 13 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Does a registered trial mean the peptide works?
No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.
What is the difference between a registered trial and published evidence?
Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.
Why do phases matter?
Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Abaloparatide is registered as an intervention. Last updated 2026-09-23.