Skip to main content
New — The Peptide Dictionary: 128 terms, explained simply
New guide — NAD+ for Anti-Aging: What the Science Says
New guide — GHK-Cu: the copper peptide for your skin
Not sure where to start? — A 60-second quiz points you to the path that fits your goal
New explainer — Semaglutide: what the research says, made simple
Browse — Peptide guides, made simple
New — The Peptide Dictionary: 128 terms, explained simply
New guide — NAD+ for Anti-Aging: What the Science Says
New guide — GHK-Cu: the copper peptide for your skin
Not sure where to start? — A 60-second quiz points you to the path that fits your goal
New explainer — Semaglutide: what the research says, made simple
Browse — Peptide guides, made simple
Easy-to-follow guides
Independent reviews
Vetted providers
Free to read

Home / Clinical trials / Linaclotide

ClinicalTrials.gov · updated 2026-09-23

Are there clinical trials for Linaclotide?

Established clinical evidence

Linaclotide has 60 registered clinical trials, including 39 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

60
Registered studies
56
Interventional trials
39
Completed
8
Currently active

Trial breakdown

By phase

Phase 316
Phase 214
Not applicable11
Phase 49
Phase 16
Early Phase 11

By status

Completed41
Unknown status5
Terminated4
Recruiting3
Withdrawn2
Active, not recruiting2
Not yet recruiting2
Enrolling by invitation1

Active trials

Most recent registered trials

How to read this. These are counts of studies registered on ClinicalTrials.gov, the US clinical trial registry. Registration is not evidence of benefit, and a registered trial may never report results. Counts are the most complete public measure of research activity, not a verdict on whether a compound works.

Frequently asked questions

Are there clinical trials for Linaclotide?

Linaclotide has 60 registered clinical trials, including 39 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

Does a registered trial mean the peptide works?

No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.

What is the difference between a registered trial and published evidence?

Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.

Why do phases matter?

Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.

Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Linaclotide is registered as an intervention. Last updated 2026-09-23.