Home / Clinical trials / Pramlintide
Are there clinical trials for Pramlintide?
Pramlintide has 64 registered clinical trials, including 43 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Trial breakdown
By phase
| Not applicable | 20 |
| Phase 2 | 19 |
| Phase 4 | 10 |
| Phase 1 | 8 |
| Phase 3 | 8 |
| Early Phase 1 | 2 |
By status
| Completed | 44 |
| Unknown status | 6 |
| Withdrawn | 5 |
| Terminated | 4 |
| Not yet recruiting | 3 |
| Active, not recruiting | 1 |
| Recruiting | 1 |
Active trials
- Postprandial Regulation of Bone Perfusion in Healthy IndividualsNot applicable · Not yet recruiting · 15 participants · University of Copenhagen · started 2026-07-19NCT07679516
- Pancreatic Polypeptide as a Modulator of Amylin- Induced Satiety in Healthy HumansNot applicable · Recruiting · 18 participants · University Hospital, Gentofte, Copenhagen · started 2026-04NCT07506369
- Amylin-Induced Migraine Attacks Without AuraNot applicable · Not yet recruiting · 21 participants · Danish Headache Center · started 2026-02NCT07340788
- Hypersensitivity to Amylin in Post-Traumatic HeadacheNot applicable · Not yet recruiting · 21 participants · Danish Headache Center · started 2026-02NCT07340775
- Multi-Center Development of a Novel Diagnostic Test for Alzheimer's DiseaseEarly Phase 1 · Active, not recruiting · 57 participants · Boston University · started 2020-02-04NCT03560960
Most recent registered trials
- Postprandial Regulation of Bone Perfusion in Healthy IndividualsNot applicable · Not yet recruiting · 15 participants · University of Copenhagen · started 2026-07-19NCT07679516
- Pancreatic Polypeptide as a Modulator of Amylin- Induced Satiety in Healthy HumansNot applicable · Recruiting · 18 participants · University Hospital, Gentofte, Copenhagen · started 2026-04NCT07506369
- Amylin-Induced Migraine Attacks Without AuraNot applicable · Not yet recruiting · 21 participants · Danish Headache Center · started 2026-02NCT07340788
- Hypersensitivity to Amylin in Post-Traumatic HeadacheNot applicable · Not yet recruiting · 21 participants · Danish Headache Center · started 2026-02NCT07340775
- Tailoring Obesity Treatment TrialPhase 2 / Phase 3 · Withdrawn · Esbjerg Hospital - University Hospital of Southern Denmark · started 2025-04-01NCT06619015
- Two Way Crossover Closed Loop Study Insulin vs Insulin and PramlintideNot applicable · Completed · 33 participants · Oregon Health and Science University · started 2024-07-12NCT06422325
- The Role of Amylin in Bone MetabolismNot applicable · Unknown status · 20 participants · Filip Krag Knop · started 2024-02-12NCT06186063
- A Fully Automated Lyumjev and Pramlintide Delivery System for Adults With Type 1 DiabetesPhase 2 / Phase 3 · Unknown status · 30 participants · McGill University Health Centre/Research Institute of the McGill University Health Centre · started 2023-11-30NCT06046417
- A Fully-closed Loop, Pramlintide and Insulin, Artificial Pancreas Clinical Trial for Adults With Type 1 DiabetesNot applicable · Completed · 12 participants · McGill University Health Centre/Research Institute of the McGill University Health Centre · started 2022-02-21NCT05199714
- Co-administration of Pramlintide and Insulin Via an Automated Dual-hormone Artificial Pancreas System in Adults With Type 1 DiabetesNot applicable · Unknown status · 26 participants · McGill University · started 2021-11-12NCT04243629
- Safety and Efficacy of BC LisPramPhase 1 · Unknown status · 16 participants · Michael Tsoukas · started 2021-07-28NCT04972175
- Alleviating Carbohydrate Counting for Patients With Type 1 Diabetes Using a Novel Insulin-plus-pramlintide Artificial PancreasNot applicable · Completed · 36 participants · McGill University · started 2020-02-14NCT04163874
Frequently asked questions
Are there clinical trials for Pramlintide?
Pramlintide has 64 registered clinical trials, including 43 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Does a registered trial mean the peptide works?
No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.
What is the difference between a registered trial and published evidence?
Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.
Why do phases matter?
Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Pramlintide is registered as an intervention. Last updated 2026-09-23.