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Are there clinical trials for Octreotide?
Octreotide has 326 registered clinical trials, including 176 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Trial breakdown
By phase
| Phase 2 | 111 |
| Phase 3 | 73 |
| Phase 1 | 49 |
| Phase 4 | 44 |
| Not applicable | 33 |
| Early Phase 1 | 7 |
By status
| Completed | 192 |
| Terminated | 39 |
| Unknown status | 31 |
| Recruiting | 30 |
| Active, not recruiting | 13 |
| Withdrawn | 12 |
| Not yet recruiting | 7 |
| No longer available | 1 |
| Suspended | 1 |
Active trials
- Human Models of Selective Insulin Resistance: Pancreatic ClampPhase 1 · Not yet recruiting · 36 participants · Columbia University · started 2027-01-01NCT06558422
- Intranasal Delivery of Octreotide for Treatment of Diabetic Macular EdemaPhase 1 · Not yet recruiting · 60 participants · University of Alabama at Birmingham · started 2026-08-31NCT06881888
- Effect of Insulin Lowering on LipogenesisPhase 1 · Recruiting · 25 participants · Columbia University · started 2026-07-01NCT07403604
- An Observational Study of Octreotide Subcutaneous Depot in Patients With AcromegalyRecruiting · 200 participants · Camurus AB · started 2026-06-05NCT07583563
- A Phase III Clinical Trial to Evaluate the Efficacy and Safety of Octreotide Long-acting Injection in Patients With AcromegalyPhase 3 · Not yet recruiting · 154 participants · CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · started 2026-05-31NCT07623824
- Octreotide Microspheres for Preventing Pancreatic FistulaPhase 3 · Not yet recruiting · 230 participants · Shanghai Zhongshan Hospital · started 2026-04-01NCT07479784
- Analysis of Optimal Treatment Sequencing of Surufatinib and Somatostatin Analogs in Neuroendocrine Tumors: A Retrospective Cohort StudyActive, not recruiting · 500 participants · West China Hospital · started 2026-03-06NCT07534371
- Hoffa's Fat Pad Impingement (HFPI)Phase 4 · Recruiting · 62 participants · Boston Children's Hospital · started 2026-03-01NCT07255248
Most recent registered trials
- Human Models of Selective Insulin Resistance: Pancreatic ClampPhase 1 · Not yet recruiting · 36 participants · Columbia University · started 2027-01-01NCT06558422
- Intranasal Delivery of Octreotide for Treatment of Diabetic Macular EdemaPhase 1 · Not yet recruiting · 60 participants · University of Alabama at Birmingham · started 2026-08-31NCT06881888
- Effect of Insulin Lowering on LipogenesisPhase 1 · Recruiting · 25 participants · Columbia University · started 2026-07-01NCT07403604
- A Phase 1 Study to Evaluate the Relative Bioavailability of Octreotide Acetate Tablets(T25) Compared to MYCAPSSA® and The Food Effect on Pharmacokinetics Of Octreotide Acetate Tablets(T25)Phase 1 · Completed · 18 participants · Triastek (Shanghai) Limited · started 2026-06-25NCT07663318
- An Observational Study of Octreotide Subcutaneous Depot in Patients With AcromegalyRecruiting · 200 participants · Camurus AB · started 2026-06-05NCT07583563
- A Phase III Clinical Trial to Evaluate the Efficacy and Safety of Octreotide Long-acting Injection in Patients With AcromegalyPhase 3 · Not yet recruiting · 154 participants · CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · started 2026-05-31NCT07623824
- Octreotide Microspheres for Preventing Pancreatic FistulaPhase 3 · Not yet recruiting · 230 participants · Shanghai Zhongshan Hospital · started 2026-04-01NCT07479784
- Analysis of Optimal Treatment Sequencing of Surufatinib and Somatostatin Analogs in Neuroendocrine Tumors: A Retrospective Cohort StudyActive, not recruiting · 500 participants · West China Hospital · started 2026-03-06NCT07534371
- Hoffa's Fat Pad Impingement (HFPI)Phase 4 · Recruiting · 62 participants · Boston Children's Hospital · started 2026-03-01NCT07255248
- 18F-AlF-NOTA-Octreotide PET in Neuroendocrine NeoplasmsNot yet recruiting · 152 participants · First Affiliated Hospital of Zhejiang University · started 2026-01-01NCT07102056
- A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin AnalogsPhase 3 · Recruiting · 119 participants · Debiopharm International SA · started 2025-11-26NCT06930625
- Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine RegimenPhase 3 · Recruiting · 141 participants · Crinetics Pharmaceuticals Inc. · started 2025-11-19NCT07087054
Frequently asked questions
Are there clinical trials for Octreotide?
Octreotide has 326 registered clinical trials, including 176 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Does a registered trial mean the peptide works?
No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.
What is the difference between a registered trial and published evidence?
Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.
Why do phases matter?
Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Octreotide is registered as an intervention. Last updated 2026-09-23.