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Are there clinical trials for Desmopressin?
Desmopressin has 125 registered clinical trials, including 64 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Trial breakdown
By phase
| Phase 4 | 29 |
| Not applicable | 26 |
| Phase 3 | 23 |
| Phase 2 | 19 |
| Phase 1 | 6 |
| Early Phase 1 | 1 |
By status
| Completed | 76 |
| Unknown status | 22 |
| Terminated | 11 |
| Recruiting | 10 |
| Enrolling by invitation | 3 |
| Active, not recruiting | 1 |
| Not yet recruiting | 1 |
| Withdrawn | 1 |
Active trials
- Bedtime Device Restriction and Desmopressin in PMNE.Not applicable · Recruiting · 140 participants · Al-Azhar University · started 2026-08-20NCT07776977
- DDAVP Effect by TEG6 in Cardiac SurgeryRecruiting · 100 participants · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · started 2026-08-01NCT07179991
- Randomized Controlled Clinical Study on the Prophylactic Intraoperative Use of Desmopressin in Complex Sellar Region TumorsPhase 4 · Enrolling by invitation · 152 participants · Zhaoyun Zhang · started 2026-06-02NCT07712328
- DDAVP for Pituitary AdenomaNot applicable · Recruiting · 22 participants · National Institute of Neurological Disorders and Stroke (NINDS) · started 2026-03-09NCT04569591
- Transfusion Reduction in High-Bleeding-Risk Cardiac Surgery With DesmopressinPhase 3 · Not yet recruiting · 112 participants · Imam Abdulrahman Bin Faisal University · started 2025-07NCT07012837
- Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot TrialPhase 3 · Recruiting · 100 participants · Hamilton Health Sciences Corporation · started 2025-06-09NCT06337838
- Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal EnuresisNot applicable · Recruiting · 40 participants · Bahçeşehir University · started 2025-03-11NCT06883851
- Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe HyponatremiaPhase 3 · Recruiting · 260 participants · Assistance Publique - Hôpitaux de Paris · started 2024-12-17NCT06020495
Most recent registered trials
- Bedtime Device Restriction and Desmopressin in PMNE.Not applicable · Recruiting · 140 participants · Al-Azhar University · started 2026-08-20NCT07776977
- DDAVP Effect by TEG6 in Cardiac SurgeryRecruiting · 100 participants · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · started 2026-08-01NCT07179991
- Randomized Controlled Clinical Study on the Prophylactic Intraoperative Use of Desmopressin in Complex Sellar Region TumorsPhase 4 · Enrolling by invitation · 152 participants · Zhaoyun Zhang · started 2026-06-02NCT07712328
- DDAVP for Pituitary AdenomaNot applicable · Recruiting · 22 participants · National Institute of Neurological Disorders and Stroke (NINDS) · started 2026-03-09NCT04569591
- Transfusion Reduction in High-Bleeding-Risk Cardiac Surgery With DesmopressinPhase 3 · Not yet recruiting · 112 participants · Imam Abdulrahman Bin Faisal University · started 2025-07NCT07012837
- Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot TrialPhase 3 · Recruiting · 100 participants · Hamilton Health Sciences Corporation · started 2025-06-09NCT06337838
- Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal EnuresisNot applicable · Recruiting · 40 participants · Bahçeşehir University · started 2025-03-11NCT06883851
- Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe HyponatremiaPhase 3 · Recruiting · 260 participants · Assistance Publique - Hôpitaux de Paris · started 2024-12-17NCT06020495
- Vitamin D Versus Desmopressin Versus Combination Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis and Vitamin D DeficiencyNot applicable · Completed · 90 participants · Ain Shams University · started 2024-12-15NCT07292753
- Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing SyndromePhase 2 · Recruiting · 140 participants · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · started 2024-12-12NCT06635629
- Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNEPhase 3 · Recruiting · 120 participants · Mansoura University · started 2024-12-01NCT07199894
- Ginkgo Biloba vs Desmopressin in Treatment of Children With Monosymptomatic Nocturnal EnuresisNot applicable · Completed · 398 participants · Menoufia University · started 2024-11-01NCT06771128
Frequently asked questions
Are there clinical trials for Desmopressin?
Desmopressin has 125 registered clinical trials, including 64 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.
Does a registered trial mean the peptide works?
No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.
What is the difference between a registered trial and published evidence?
Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.
Why do phases matter?
Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Desmopressin is registered as an intervention. Last updated 2026-09-23.