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Home / Clinical trials / Tirzepatide

ClinicalTrials.gov · updated 2026-09-23

Are there clinical trials for Tirzepatide?

Established clinical evidence

Tirzepatide has 289 registered clinical trials, including 73 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

289
Registered studies
239
Interventional trials
73
Completed
191
Currently active

Trial breakdown

By phase

Phase 277
Phase 354
Phase 447
Phase 138
Not applicable27
Early Phase 16

By status

Recruiting96
Completed89
Not yet recruiting58
Active, not recruiting32
Enrolling by invitation5
Unknown status4
Withdrawn4
Terminated1

Active trials

Most recent registered trials

How to read this. These are counts of studies registered on ClinicalTrials.gov, the US clinical trial registry. Registration is not evidence of benefit, and a registered trial may never report results. Counts are the most complete public measure of research activity, not a verdict on whether a compound works.

Frequently asked questions

Are there clinical trials for Tirzepatide?

Tirzepatide has 289 registered clinical trials, including 73 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

Does a registered trial mean the peptide works?

No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.

What is the difference between a registered trial and published evidence?

Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.

Why do phases matter?

Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.

Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Tirzepatide is registered as an intervention. Last updated 2026-09-23.