New — The Peptide Dictionary: 128 terms, explained simply
New guide — NAD+ for Anti-Aging: What the Science Says
New guide — GHK-Cu: the copper peptide for your skin
Not sure where to start? — A 60-second quiz points you to the path that fits your goal
New explainer — Semaglutide: what the research says, made simple
Browse — Peptide guides, made simple
New — The Peptide Dictionary: 128 terms, explained simply
New guide — NAD+ for Anti-Aging: What the Science Says
New guide — GHK-Cu: the copper peptide for your skin
Not sure where to start? — A 60-second quiz points you to the path that fits your goal
New explainer — Semaglutide: what the research says, made simple
Browse — Peptide guides, made simple
Skip to main content
Tools

Weight Loss

Start here: GLP-1s for weight loss →

GLP-1 medications, what they cost, and living with them.

Get startedCompare providers27 telehealth providers, scored the same way — price, what's included, and who each one suits.See the comparison →

Sexual Health

Start here: sexual wellness →

ED, low desire, and what the approved options actually are.

Get startedCompare providersSexual wellness providers scored on the same footing — price, format and what's actually included.See the comparison →

Hair Loss

Start here: hair thinning →

Why hair thins, and what has evidence behind it.

Get startedWhat actually worksSix copper peptide serums compared on formula, strength and price.See the comparison →

Hormones

Start here: hormones and aging →

Growth hormone, PCOS, and the peptides people ask about.

Get startedWhat the trials showEvery peptide we cover, with the human trials behind it — or the absence of them.Browse the evidence →

Peptides & Longevity

Start here: what are peptides? →

The molecules, the evidence, and where regulation stands.

Get startedOriginal researchOur own analysis of primary government data — full methodology and datasets published.See the research →

Medications

Start here: every molecule we cover →

One page per medicine — what it is, what it costs, what to expect.

Get startedPeptides A–ZEvery peptide we cover, in one list, with where each one stands.Browse A–Z →
Easy-to-follow guides
Independent reviews
Vetted providers
Free to read

Home / Clinical trials / Tirzepatide

ClinicalTrials.gov · updated 2026-11-09

Are there clinical trials for Tirzepatide?

Established clinical evidence

Tirzepatide has 312 registered clinical trials, including 76 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

312
Registered studies
255
Interventional trials
76
Completed
209
Currently active

Trial breakdown

By phase

Phase 280
Phase 360
Phase 450
Phase 141
Not applicable30
Early Phase 16

By status

Recruiting103
Completed92
Not yet recruiting62
Active, not recruiting38
Enrolling by invitation6
Unknown status5
Withdrawn5
Terminated1

Active trials

Most recent registered trials

How to read this. These are counts of studies registered on ClinicalTrials.gov, the US clinical trial registry. Registration is not evidence of benefit, and a registered trial may never report results. Counts are the most complete public measure of research activity, not a verdict on whether a compound works.

What Tirzepatide is being studied for

Most studied conditions

Obesity113
Overweight36
Obesity & Overweight26
Type 2 Diabetes26
Diabetes Mellitus, Type 219
Type 2 Diabetes Mellitus12
Obesity (Disorder)9
Healthy9

Who is running the studies

Eli Lilly and Company (82)
Brigham and Women's Hospital (11)
The Cleveland Clinic (6)
Novo Nordisk A/S (6)
Mayo Clinic (4)
University of Texas Southwestern Medical Center (4)
People enrolled across all studies24,792,038
Completed studies that posted results47 of 76, 62%

Counted from ClinicalTrials.gov registrations, checked 2026-11-09.

Peptides with a similar weight of evidence

Ordered by how far the registered research has progressed.

Frequently asked questions

Are there clinical trials for Tirzepatide?

Tirzepatide has 312 registered clinical trials, including 76 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

Does a registered trial mean the peptide works?

No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.

What is the difference between a registered trial and published evidence?

Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.

Why do phases matter?

Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.

Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Tirzepatide is registered as an intervention. Last updated 2026-11-09.

Related data

More from Peptides.io