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Home / Clinical trials / Semaglutide

ClinicalTrials.gov · updated 2026-11-09

Are there clinical trials for Semaglutide?

Established clinical evidence

Semaglutide has 801 registered clinical trials, including 285 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

801
Registered studies
651
Interventional trials
285
Completed
377
Currently active

Trial breakdown

By phase

Phase 3186
Phase 2155
Phase 1127
Phase 4123
Not applicable78
Early Phase 19

By status

Completed355
Recruiting179
Not yet recruiting107
Active, not recruiting71
Unknown status44
Enrolling by invitation20
Withdrawn15
Terminated9
Suspended1

Active trials

Most recent registered trials

How to read this. These are counts of studies registered on ClinicalTrials.gov, the US clinical trial registry. Registration is not evidence of benefit, and a registered trial may never report results. Counts are the most complete public measure of research activity, not a verdict on whether a compound works.

What Semaglutide is being studied for

Most studied conditions

Obesity200
Diabetes Mellitus, Type 2173
Diabetes71
Type 2 Diabetes69
Overweight57
Obesity & Overweight33
Healthy28
Weight Loss16

Who is running the studies

Novo Nordisk A/S (265)
Brigham and Women's Hospital (19)
University of Colorado, Denver (10)
Eli Lilly and Company (10)
Mayo Clinic (6)
Vanderbilt University Medical Center (6)
People enrolled across all studies28,413,067
Completed studies that posted results112 of 285, 39%

Counted from ClinicalTrials.gov registrations, checked 2026-11-09.

Peptides with a similar weight of evidence

Ordered by how far the registered research has progressed.

Frequently asked questions

Are there clinical trials for Semaglutide?

Semaglutide has 801 registered clinical trials, including 285 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

Does a registered trial mean the peptide works?

No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.

What is the difference between a registered trial and published evidence?

Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.

Why do phases matter?

Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.

Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Semaglutide is registered as an intervention. Last updated 2026-11-09.

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