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Home / Clinical trials / Semaglutide

ClinicalTrials.gov · updated 2026-09-23

Are there clinical trials for Semaglutide?

Established clinical evidence

Semaglutide has 758 registered clinical trials, including 275 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

758
Registered studies
618
Interventional trials
275
Completed
350
Currently active

Trial breakdown

By phase

Phase 3179
Phase 2149
Phase 1125
Phase 4112
Not applicable72
Early Phase 18

By status

Completed343
Recruiting169
Not yet recruiting99
Active, not recruiting63
Unknown status41
Enrolling by invitation19
Withdrawn14
Terminated9
Suspended1

Active trials

Most recent registered trials

How to read this. These are counts of studies registered on ClinicalTrials.gov, the US clinical trial registry. Registration is not evidence of benefit, and a registered trial may never report results. Counts are the most complete public measure of research activity, not a verdict on whether a compound works.

Frequently asked questions

Are there clinical trials for Semaglutide?

Semaglutide has 758 registered clinical trials, including 275 completed interventional studies and trials reaching Phase 4. Its use in humans is supported by established registered clinical evidence.

Does a registered trial mean the peptide works?

No. Registration means a study was formally listed before or during the research. It says nothing about the result. A completed trial can find no benefit, and many registered studies are never published.

What is the difference between a registered trial and published evidence?

Registration records that a study exists. Publication reports what it found. This page counts registrations, which is the more complete picture of research activity, but it is not a measure of proven effectiveness.

Why do phases matter?

Phase 1 tests safety in a small group. Phase 2 looks for early signs of effect. Phase 3 tests effectiveness against a comparator in a large group, and is what regulators normally require. Phase 4 studies happen after approval. A compound with only Phase 1 trials has not been shown to work.

Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine. Studies where Semaglutide is registered as an intervention. Last updated 2026-09-23.